Well, it’s probably not the sulfites, right? Indeed, it probably is not. The
most likely culprits are histamines in wine. Red wines have higher levels of
histamines than whites, since the histamines are in the skins of the wine and
red wines spend time macerating on their skins to extract pigment, tannin,
flavors, and, yes, histamines.
Those same tannins and flavonoids tend to
help to preserve red wines, resulting in many white wines with higher levels of
sulfites than red wines. So, if you’re getting a headache after drinking red
wine, it is likely a reaction to the histamines, which can be prevented by
taking an antihistamine before starting to drink.
Source: snooth.com
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